Effects of MgSO4 on ventricular arrhythmias induced by digitalis.
نویسندگان
چکیده
منابع مشابه
CaMKII Mediates Digitalis - Induced Arrhythmias
Background Digitalis-induced Na accumulation results in an increase in Cai via the Na/Ca exchanger leading to enhanced SR Ca load, responsible for the positive inotropic and toxic arrhythmogenic effects of glycosides. Digitalis-induced increase in Cai could also activate CaMKII which has been shown to have proarrhythmic effects. Here we investigate whether CaMKII underlies digitalis-induced arr...
متن کاملStudies on magnesium's mechanism of action in digitalis-induced arrhythmias.
The mechanism by which magnesium affects digitalis-induced arrhythmias was studied in dogs with and without beta-receptor blockade. Digoxin was infused at a rate of 2.5mug/kg/min until ventricular tachycardia developed, then half the animals were given MgSO4, the other half saline. In animals given MgSO4, sinus rhythm was immediately re-established; in animals given saline, ventricular tachycar...
متن کاملCaMKII Mediates Digitalis - Induced Arrhythmias Running title :
Background Digitalis-induced Na accumulation results in an increase in Cai via the Na/Ca exchanger leading to enhanced SR Ca load, responsible for the positive inotropic and toxic arrhythmogenic effects of glycosides. Digitalis-induced increase in Cai could also activate CaMKII which has been shown to have proarrhythmic effects. Here we investigate whether CaMKII underlies digitalis-induced arr...
متن کاملMagnesium's Mechanism of Action in Digitalis-induced Arrhythmias
The mechanism by which magnesium affects digitalis-induced arrhythmias was studied in dogs with and without beta-receptor blockade. Digoxin was infused at a rate of 2.5,ug/kg/min until ventricular tachycardia developed, then half the animals were given MgSO4, the other half saline. In animals given MgSO4, sinus rhythm was immediately re-established; in animals given saline, ventricular tachycar...
متن کاملEffects of left ventricular assist device therapy on ventricular arrhythmias.
OBJECTIVES In a retrospective study, we sought to evaluate the effect of left ventricular assist device (LVAD) therapy on ventricular tachyarrhythmias in patients with advanced congestive heart failure. BACKGROUND Despite the increasing use of LVAD as a bridge to cardiac transplantation, our knowledge regarding its effect on ventricular arrhythmias is currently limited to small series. Little...
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ژورنال
عنوان ژورنال: Japanese Journal of Electrocardiology
سال: 1995
ISSN: 1884-2437,0285-1660
DOI: 10.5105/jse.15.227